The website is under development. Apologies for any disappointment. Coming soon.

Is red wine really good for us ?

This is a use base post which consists of scientific terminologies but not biochemistry. We recommend familiarity with some biology, and chemistry fundamentals for better understanding. A research review by Dhruva Sharma (A Non-practising forensic scientist and a content creator) with the TWDOC team.

HEALTHCARE

10/6/20234 min read

In the near future, there will be some wholesome and constructive discussions regarding the long-term effects of resveratrol and how more long-term, double-blind, randomised clinical trials are needed to provide us with the relevant data we need to determine if it is truly beneficial to human health or absolutely detrimental. Therefore, without giving it a second thought, we will be focusing closely on understanding the effectiveness, advantages, and potential drawbacks for people, taking into account both short- and long-term consumption of red wine's main constituent, resveratrol.

Red wine has been a popular beverage for generations, and several studies have looked into the potential health advantages of moderate red wine use. One of the main substances credited with these health advantages is resveratrol, a polyphenol present in red wine. But recent research has raised questions regarding resveratrol's side effects, particularly those that arise from repeated intake. In this article, we will examine the advantages and disadvantages of resveratrol.

Here's a second look


Resveratrol, if taken in heavy doses, will cause harm to the body and mind in the long term, and we have research done on mice to support this argument. Earlier, people used to think that resveratrol would give us the ultimate longevity dose we needed and help us keep our heart and brain young, but the latest reports came from the research done in early 2020 and forward, which really made me address this concern here. Is it true?

So what are these reports, and why should we take a second look? Well, one of the most significant concerns with resveratrol consumption is its potential to cause liver toxicity. A study published in the Journal of Agricultural and Food Chemistry in 2020 found that high doses of resveratrol can cause liver damage in mice. The risk of liver damage associated with resveratrol use is one of the biggest worries. This emphasises the significance of exercising caution while consuming functional foods or dietary supplements containing resveratrol.

Another potential issue with resveratrol consumption is its interference with drug metabolism. Resveratrol has been shown to inhibit the metabolism of some drugs, including statins, which are commonly prescribed to lower cholesterol. A study published in the Journal of Clinical Pharmacology in 2018 found that resveratrol inhibits the metabolism of simvastatin, potentially leading to increased levels of the drug in the body.

Resveratrol has also been shown to have hormonal effects, which could be harmful in some cases. A study published in the journal Nutrients in 2020 found that resveratrol can disrupt the balance of sex hormones in men and women. Caution should be taken when using resveratrol as a dietary supplement. Although the long-term effects of resveratrol consumption are still being studied, some potential side effects have been reported. These include headaches, nausea, and digestive issues.

Fortunately, it is not all hail Mary; there are some positives to all of this systematic chaos.

the positive effects

Despite the potential negative effects of resveratrol, there are also potential benefits to its consumption. One of its most well-known benefits is its positive effects on cardiovascular health. A study published in the journal Nutrients in 2019 found that resveratrol supplementation reduced blood pressure and improved arterial function in overweight and obese individuals.

Another potential benefit of resveratrol is its anti-cancer effects. A review published in the journal Nutrients in 2020 found that resveratrol can inhibit the growth of cancer cells and induce apoptosis (programmed cell death) in some cancers.

Finally, resveratrol has been suggested to promote longevity. A study published in the journal Nature in 2013 found that resveratrol supplementation extended lifespan and improved health in mice on a high-calorie diet.

Conclusion

It is important to note that the research on resveratrol is ongoing, and more studies are needed to fully understand its potential benefits and risks. For intellectually, experienced professionals, it is essential to stay informed on the latest research and to consult with a healthcare professional before using resveratrol as a dietary supplement.

While there are some potential negative effects associated with resveratrol, these are generally only observed with excessive consumption or long-term use. As with any supplement or medication, it is important to weigh the potential benefits against the potential risks and to discuss any concerns with a healthcare professional. Overall, resveratrol has shown promising potential benefits for human health, particularly in its antioxidant, anti-inflammatory, cardiovascular, and potential cancer-fighting properties. However, more research is needed to fully understand the effects of resveratrol on human health.

References
  1. de la Lastra CA, Villegas I. Resveratrol as an antioxidant and pro-oxidant agent: mechanisms and clinical implications. Biochem Soc Trans. 2007;35(Pt 5):1156-1160.

  2. Bhat KP, Pezzuto JM. Cancer chemopreventive activity of resveratrol. Ann N Y Acad Sci. 2002;957:210-229.

  3. Sahebkar A, Serban C, Ursoniu S, et al. Effect of resveratrol supplementation on plasma lipids: a systematic review and meta-analysis of randomized controlled trials. Nutr Rev. 2015;73(12):822-833.

Check out the blog section for more informative and intuitive articles, and feel free to look through the sources for citations. Till then, remember to take deep breaths and spread love.

And don't forget to sign up for the newsletter to get these kinds of articles personally delivered to you.

clear wine glass
clear wine glass
a person drinking a glass of wine
a person drinking a glass of wine

Quality, not quantity

Quality has become a habit for us. It's not only something we aspire to; we live by this philosophy every day. Every piece of information supplied has been fact-checked, vetted, and referenced so that you may learn and explore with us.

We all can influence the informational absorption of relevant material to make it more legitimate, worthy, and needed.

man in black hoodie wearing black mask
man in black hoodie wearing black mask
text
text